Fish oil contains omega-3 fatty acid which are docosahexaenoic acid and eicosapentaenoic acid. It is used in adults to provide calories and is used to treat hypertriglyceridemia in addition with healthy diet.
This product reduces inflammation and helps to treat cardiovascular diseases, Decreases oxidative stress.

Indications

⇒ Myocardial infarction
⇒ Hypertriglyceridemia
⇒ Dietary and nutrition therapies

Mechanism of Action

Docosahexaenoic acid present in the retina, brain. It is helps in the formation eicosanoids which are signalling molecule whereas eicosanoids are involved in the cardiovascular, endocrine and immune system. They increase cellular metabolism thereby reduces the triglyceride level in the blood.

Pharmacokinetics

Absorption- It is absorbed orally
Protein Binding- Eicosapentaenoic acid shows binding to proteins
Metabolism- It undergoes oxidation in the liver
Excretion- It is excreted renally

Side Effects

⇒ Belching
⇒ Heartburn
⇒ Nausea
⇒ Loose stools
⇒ Rashes
⇒ Nose bleeding

Contraindications

⇒ Contraindicated in bleeding disorders

Drug Interactions

⇒ Anticoagulant
⇒ Antiplatelets